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20 angezeigte Treffer · Seite 1, keine Gesamtzahl für „tipranavir“
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Aptivus · 4.5 · 15 Inhibition of CYP 3A4 by tipranavir/r HMG CoA reductase inhibitors Atorvastatin 10 mg QD Atorvastatin Cmax
Eintrag öffnenAptivus · 4.5 · 16 metabolising enzymes by St John’s wort is expected to John’s wort. substantially decrease tipranavir and ri
Eintrag öffnenAptivus · 4.5 · 18 Antithrombotics Warfarin 10 mg QD First-dose tipranavir/r: Aptivus, co-administered with S-warfarin Cmax ↔
Eintrag öffnenAptivus · 4.5 · 21 CYP 3A4 inhibition by tipranavir/r Others Theophylline Based on data from the cocktail Theophylline plasma
Eintrag öffnenAptivus · 4.5 · 8 In vitro studies show that tipranavir is a substrate and also an inhibitor of P-gp.
Eintrag öffnenAptivus · 4.5 · A cocktail study was conducted in 16 healthy volunteers with twice-daily 500 mg tipranavir with 200 mg ritonav
Eintrag öffnenAptivus · 4.5 · Antacids aluminium- and Tipranavir Cmax ↓ 25% Dosing of Aptivus, co- magnesium-based antacid Tipranavir AUC ↓
Eintrag öffnenAptivus · 4.5 · Based on theoretical considerations, tipranavir or ritonavir concentrations might increase upon co-administrat
Eintrag öffnenAptivus · 4.5 · Co-administration of Aptivus and agents that induce CYP3A and/or P-gp may decrease tipranavir concentrations a
Eintrag öffnenAptivus · 4.5 · Digoxin 0.25 mg QD po First-dose tipranavir/r Digoxin Cmax ↑ 93% Digoxin AUC ↑ 91%
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 2D6 by tipranavir/r Antihistamines Astemizole Based on theoretical The concomitant use of Ap
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 2D6 by tipranavir/r Digoxin 0.25 mg QD iv First-dose tipranavir/r Monitoring of digoxin seru
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 3A4 and CYP 2D6 by tipranavir/r Endothelin receptor antagonists Bosentan Based on theoretica
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 3A4 by tipranavir/r. Oral contraceptives / Oestrogens Ethinyl oestradiol Ethinyl oestradiol
Eintrag öffnenAptivus · 4.5 · Mechanism unknown Meperidine Tipranavir, co-administered with Dosage increase and long-term No interaction stu
Eintrag öffnenAptivus · 4.5 · Metabolic profile of tipranavir Tipranavir is a substrate, an inducer and an inhibitor of cytochrome P450 CYP3
Eintrag öffnenAptivus · 4.5 · No clinically significant change is observed in tipranavir PK parameters. Rifampicin Co-administration of prot
Eintrag öffnenAptivus · 4.5 · Pharmacokinetic enhancer Cobicistat and cobicistat- When co-administered, tipranavir Aptivus/ritonavir should
Eintrag öffnenAptivus · 4.5 · Steady-state tipranavir/r Digoxin Cmax ↓ 38% Digoxin AUC ↔ Trazodone In a pharmacokinetic study The combinatio
Eintrag öffnenAptivus · 4.5 · Studies in human liver microsomes indicated tipranavir is an inhibitor of CYP 1A2, CYP 2C9, CYP 2C19 and CYP 2
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