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Eintrag öffnenAfinitor · 4.5 · 8 Table 2 Effects of other active substances on everolimus
Eintrag öffnenAfinitor · 4.5 · Active substance by Interaction – Change in Recommendations concerning interaction Everolimus AUC/Cmax co-admi
Eintrag öffnenAfinitor · 4.5 · Agents whose plasma concentration may be altered by everolimus
Eintrag öffnenAfinitor · 4.5 · CYP3A4 and PgP inducers decreasing everolimus concentrations
Eintrag öffnenAfinitor · 4.5 · CYP3A4 and PgP inhibitors increasing everolimus concentrations
Eintrag öffnenAfinitor · 4.5 · Co-administration of everolimus and depot octreotide increased octreotide Cmin with a geometric mean ratio (ev
Eintrag öffnenAfinitor · 4.5 · Co-administration of everolimus and exemestane increased exemestane Cmin and C2h by 45% and 64%, respectively.
Eintrag öffnenAfinitor · 4.5 · Everolimus is a substrate of CYP3A4, and also a substrate and moderate inhibitor of PgP. Therefore, absorption
Eintrag öffnenAfinitor · 4.5 · Potentiation of radiation treatment toxicity has been reported in patients receiving everolimus (see sections
Eintrag öffnenAfinitor · 4.5 · Substances that are inducers of CYP3A4 or PgP may decrease everolimus blood concentrations by increasing metab
Eintrag öffnenAfinitor · 4.5 · Substances that are inhibitors of CYP3A4 or PgP may increase everolimus blood concentrations by decreasing met
Eintrag öffnenAfinitor · 4.8 · 13 In clinical studies and post-marketing spontaneous reports, everolimus has been associated with cases of PJ
Eintrag öffnenAfinitor · 4.8 · In clinical studies and post-marketing spontaneous reports, everolimus has been associated with cases of ameno
Eintrag öffnenAfinitor · 4.8 · In clinical studies and post-marketing spontaneous reports, everolimus has been associated with renal failure
Eintrag öffnenAfinitor · 4.8 · In clinical studies and post-marketing spontaneous reports, everolimus has been associated with serious cases
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