Glycyrrhiza glabra L. (Gancao) · interaction review discussion

Plants Containing Coumarin-like Ingredients Similar to Warfarin, Producing a Synergistic Effect

Quellenbefund mit unverändertem Untersuchungskontext. Klinischer Schweregrad: nicht bewertet.

Glycyrrhiza glabra L. (Gancao): The coumarin derivatives in Glycyrrhiza glabra L. (Chen et al., 2018) may show antiplatelet activity by increasing intra-platelet cAMP. However, animal tests have also shown that Glycyrrhiza glabra L. activates pregnane X receptors (PXR) and increases the clearance of warfarin, thereby reducing its anticoagulant effect, so the mechanism of interaction between Glycyrrhiza glabra L. and warfarin requires further investigation.

Befund HOS-368752 · warfarin · HOS-085950 · Originalquelle ↗

Interaction Between Chinese Medicine and Warfarin: Clinical and Research Update ↗

Copyright © 2021 Zhuang, Liu, Zhao, Sun, He, Wang, Jia, Lin, Chu and Xi. Interaction Between Chinese Medicine and Warfarin: Clinical and Research Update. DOI: 10.3389/fphar.2021.751107 · CC BY 4.0

Quellen-Hash: b46c221ac01dd09600094fcfc243f39e7e1846720f413ea49157075cd642ed78

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