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Eigener Quellenstand, abgerufen am 27.10.2026. Die Zuordnung zum Pflanzenprofil beruht auf der übereinstimmenden Überschrift und Abschnittskennung des Herausgebers.

There are uncertainties about whether ginseng might interact with certain medications, such as calcium channel blockers and other high blood pressure medications, as well as statin medications and some antidepressants. Studies on the effect of Asian ginseng on the anticoagulant warfarin have had mixed results.

Abschnitt im NCCIH-Fachüberblick ↗

Dokument SHA-256: 80a7c442dbd3644dc6a54b986a8cfed8061d02d7653f7f03616f63f2c74f9190

Die Quelle beschreibt uneinheitliche Studienergebnisse. Daraus wird keine eindeutige Wirkungsrichtung abgeleitet.

There are uncertainties about whether ginseng might interact with certain medications, such as calcium channel blockers and other high blood pressure medications, as well as statin medications and some antidepressants. Studies on the effect of Asian ginseng on the anticoagulant warfarin have had mixed results.

warfarin · HOS-085950 · Beziehung HOS-368667 · Originalquelle ↗

Asian Ginseng · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 517–828 (Unicode-Codepoints).

Eigener Quellenstand, abgerufen am 27.10.2026. Die Zuordnung zum Pflanzenprofil beruht auf der übereinstimmenden Überschrift und Abschnittskennung des Herausgebers.

Preliminary studies suggest that taking chamomile along with oral contraceptives might decrease the effects of oral contraceptives. Interactions between chamomile and some drugs metabolized by the liver and warfarin have been reported, and there are theoretical reasons to suspect that chamomile might interact with other drugs as well, such as sedatives.

Abschnitt im NCCIH-Fachüberblick ↗

Dokument SHA-256: 80a7c442dbd3644dc6a54b986a8cfed8061d02d7653f7f03616f63f2c74f9190

Chamomile is likely safe when used orally in amounts commonly found in teas and other foods. It is possibly safe when used by adults and children orally for medicinal purposes over the short term. Using chamomile on the skin in adults and children or as an oral rinse for medicinal purposes is possibly safe at certain doses and over the short term. Side effects are uncommon and may include nausea, dizziness, and allergic reactions, including severe hypersensitivity reactions and anaphylaxis, in some people. If used near the eyes, chamomile might cause eye irritation. People are more likely to experience allergic reactions to chamomile if they’re allergic to related plants such as ragweed, chrysanthemums, marigolds, or daisies. Chamomile might have some of the same effects as estrogen. Preliminary studies suggest that taking chamomile along with birth control pills might decrease the effects of birth control pills. In addition, chamomile might worsen any condition that is sensitive to exposure to estrogen, such as breast or uterine cancer. Interactions between chamomile and some drugs metabolized by the liver and warfarin (a blood thinner) have been reported, and there are theoretical reasons to suspect that chamomile might interact with other drugs as well, such as sedatives. If you take any type of medicine, talk with your health care provider before using chamomile or other herbal products; some herbs and medicines interact in harmful ways. Little is known about whether it’s safe to use chamomile during pregnancy or while breastfeeding.

warfarin · HOS-085950 · Beziehung HOS-287139 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 1806–3369 (Unicode-Codepoints).

Preliminary studies suggest that taking chamomile along with oral contraceptives might decrease the effects of oral contraceptives. Interactions between chamomile and some drugs metabolized by the liver and warfarin have been reported, and there are theoretical reasons to suspect that chamomile might interact with other drugs as well, such as sedatives.

warfarin · HOS-085950 · Beziehung HOS-368673 · Originalquelle ↗

Chamomile · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 5238–5593 (Unicode-Codepoints).

Eigener Quellenstand, abgerufen am 27.10.2026. Die Zuordnung zum Pflanzenprofil beruht auf der übereinstimmenden Überschrift und Abschnittskennung des Herausgebers.

There is conflicting evidence about whether cranberry interacts with the anticoagulant warfarin.

Abschnitt im NCCIH-Fachüberblick ↗

Dokument SHA-256: 80a7c442dbd3644dc6a54b986a8cfed8061d02d7653f7f03616f63f2c74f9190

Cranberry taken orally (by mouth) is generally thought to be safe. However, if consumed in very large amounts, cranberry can cause stomach upset and diarrhea, particularly in young children. People who think they have a UTI should see a health care provider for diagnosis and treatment. Don’t use cranberry products instead of a proven treatment for a UTI. There is conflicting evidence about whether cranberry interacts with the anticoagulant (blood thinner) warfarin. If you take warfarin or any other medicine, talk with your health care provider before using cranberry or other herbal products; some herbs and medicines interact in harmful ways. Some studies of the use of cranberry during pregnancy or while breastfeeding suggest it is safe in amounts commonly found in food, but the evidence is not conclusive for use in larger amounts. If you’re considering using cranberry while pregnant or breastfeeding, consult your health care provider.

warfarin · HOS-085950 · Beziehung HOS-368686 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2677–3625 (Unicode-Codepoints).

Cranberry taken orally (by mouth) is generally thought to be safe. However, if consumed in very large amounts, cranberry can cause stomach upset and diarrhea, particularly in young children. People who think they have a UTI should see a health care provider for diagnosis and treatment. Don’t use cranberry products instead of a proven treatment for a UTI. There is conflicting evidence about whether cranberry interacts with the anticoagulant (blood thinner) warfarin. If you take warfarin or any other medicine, talk with your health care provider before using cranberry or other herbal products; some herbs and medicines interact in harmful ways. Some studies of the use of cranberry during pregnancy or while breastfeeding suggest it is safe in amounts commonly found in food, but the evidence is not conclusive for use in larger amounts. If you’re considering using cranberry while pregnant or breastfeeding, consult your health care provider.

warfarin · HOS-085950 · Beziehung HOS-368687 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2677–3625 (Unicode-Codepoints).

Die Quelle beschreibt uneinheitliche Studienergebnisse. Daraus wird keine eindeutige Wirkungsrichtung abgeleitet.

There is conflicting evidence about whether cranberry interacts with the anticoagulant warfarin.

warfarin · HOS-085950 · Beziehung HOS-368688 · Originalquelle ↗

Cranberry · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 8089–8185 (Unicode-Codepoints).

Eigener Quellenstand, abgerufen am 27.10.2026. Die Zuordnung zum Pflanzenprofil beruht auf der übereinstimmenden Überschrift und Abschnittskennung des Herausgebers.

Taking Ginkgo biloba with warfarin is associated with increased risk for major bleeding events compared to warfarin alone. Concomitant use of Ginkgo biloba preparations and efavirenz (a non-nucleoside reverse transcriptase inhibitor) is not recommended.

Abschnitt im NCCIH-Fachüberblick ↗

Dokument SHA-256: 80a7c442dbd3644dc6a54b986a8cfed8061d02d7653f7f03616f63f2c74f9190

For most adults, ginkgo leaf extracts are likely to be safe when taken orally in moderate amounts. They have been used safely in research studies lasting as long as 6 years. Fresh ginkgo seeds are toxic when consumed orally, and serious side effects have also occurred in people who consumed roasted ginkgo seeds or the crude ginkgo plant. Ginkgo leaf extract is generally well tolerated; the most common side effects are dizziness, gastrointestinal symptoms, and headache. Ginkgo may increase the risk of bleeding in people who are taking anticoagulant drugs, such as warfarin. Ginkgo may also interact with other drugs. If you take any type of medicine, talk with your health care provider before using ginkgo or other herbal products; some herbs and medicines interact in harmful ways. Ginkgo may be unsafe for use during pregnancy. It might cause early labor or extra bleeding during delivery if used near that time. Little is known about whether it’s safe to use ginkgo while breastfeeding.

warfarin · HOS-085950 · Beziehung HOS-287126 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2841–3836 (Unicode-Codepoints).

Taking Ginkgo biloba with warfarin is associated with increased risk for major bleeding events compared to warfarin alone. Concomitant use of Ginkgo biloba preparations and efavirenz (a non-nucleoside reverse transcriptase inhibitor) is not recommended.

warfarin · HOS-085950 · Beziehung HOS-368668 · Originalquelle ↗

Ginkgo · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 10584–10837 (Unicode-Codepoints).

Taking Ginkgo biloba with warfarin is associated with increased risk for major bleeding events compared to warfarin alone. Concomitant use of Ginkgo biloba preparations and efavirenz (a non-nucleoside reverse transcriptase inhibitor) is not recommended.

efavirenz · HOS-087947 · Beziehung HOS-368669 · Originalquelle ↗

Ginkgo · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 10584–10837 (Unicode-Codepoints).

Eigener Quellenstand, abgerufen am 27.10.2026. Die Zuordnung zum Pflanzenprofil beruht auf der übereinstimmenden Überschrift und Abschnittskennung des Herausgebers.

St. John’s wort has an overall high risk of drug interaction because it is a potent inducer of both cytochrome P-450 enzymes and intestinal P-glycoprotein. Clinically significant interactions between St. John’s wort and the immunosuppressant drug cyclosporine, the antiretroviral agent indinavir, oral contraceptives, warfarin, digoxin, and benzodiazepines, among others, have been documented. Taking St. John’s wort with certain antidepressants may lead to increased serotonin-related side effects, which may be potentially serious.

Abschnitt im NCCIH-Fachüberblick ↗

Dokument SHA-256: 80a7c442dbd3644dc6a54b986a8cfed8061d02d7653f7f03616f63f2c74f9190

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

amitriptyline · HOS-085911 · Beziehung HOS-368717 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

bupropion · HOS-086329 · Beziehung HOS-368718 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

cyclosporine · HOS-084512 · Beziehung HOS-368719 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

phenytoin · HOS-084531 · Beziehung HOS-368720 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

carbamazepine · HOS-085618 · Beziehung HOS-368721 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

digoxin · HOS-086172 · Beziehung HOS-368722 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

ivabradine · HOS-109426 · Beziehung HOS-368723 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

indinavir · HOS-084518 · Beziehung HOS-368724 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

nevirapine · HOS-088064 · Beziehung HOS-368725 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

irinotecan · HOS-112102 · Beziehung HOS-368726 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

imatinib · HOS-110212 · Beziehung HOS-368727 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

docetaxel · HOS-084505 · Beziehung HOS-368728 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

warfarin · HOS-085950 · Beziehung HOS-368729 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

For most adults who are not taking any kind of medicine, St. John’s wort appears to be safe when used for up to 12 weeks, and some studies indicate that it can be used safely for a year or more. If taken orally in large doses or applied to the skin, St. John’s wort might cause severe skin reactions after sun exposure. Other side effects can include diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. If you take any type of medicine, talk with your health care provider before using St. John’s wort or other herbal products; some herbs and medicines interact in harmful ways. For example, St. John’s wort can weaken the effects of many medicines, including crucially important medicines such as: Some antidepressants, including amitriptyline and bupropion Birth control pills Cyclosporine, which prevents the body from rejecting transplanted organs Some drugs used to prevent seizures, including phenytoin and carbamazepine Some heart medications, including digoxin and ivabradine Some HIV drugs, including indinavir and nevirapine Some cancer medications, including irinotecan, imatinib, and docetaxel Warfarin, an anticoagulant (blood thinner) Certain statins, including simvastatin In addition, taking St. John’s wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious. It may be unsafe to use St. John’s wort during pregnancy because it may increase the risk of birth defects. Breastfeeding infants of mothers who take St. John’s wort can experience colic, drowsiness, and lethargy.

simvastatin · HOS-086158 · Beziehung HOS-368730 · Originalquelle ↗

Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 2351–3993 (Unicode-Codepoints).

St. John’s wort has an overall high risk of drug interaction because it is a potent inducer of both cytochrome P-450 enzymes and intestinal P-glycoprotein. Clinically significant interactions between St. John’s wort and the immunosuppressant drug cyclosporine, the antiretroviral agent indinavir, oral contraceptives, warfarin, digoxin, and benzodiazepines, among others, have been documented. Taking St. John’s wort with certain antidepressants may lead to increased serotonin-related side effects, which may be potentially serious.

cyclosporine · HOS-084512 · Beziehung HOS-368731 · Originalquelle ↗

St. John's Wort · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 18082–18615 (Unicode-Codepoints).

St. John’s wort has an overall high risk of drug interaction because it is a potent inducer of both cytochrome P-450 enzymes and intestinal P-glycoprotein. Clinically significant interactions between St. John’s wort and the immunosuppressant drug cyclosporine, the antiretroviral agent indinavir, oral contraceptives, warfarin, digoxin, and benzodiazepines, among others, have been documented. Taking St. John’s wort with certain antidepressants may lead to increased serotonin-related side effects, which may be potentially serious.

indinavir · HOS-084518 · Beziehung HOS-368732 · Originalquelle ↗

St. John's Wort · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 18082–18615 (Unicode-Codepoints).

St. John’s wort has an overall high risk of drug interaction because it is a potent inducer of both cytochrome P-450 enzymes and intestinal P-glycoprotein. Clinically significant interactions between St. John’s wort and the immunosuppressant drug cyclosporine, the antiretroviral agent indinavir, oral contraceptives, warfarin, digoxin, and benzodiazepines, among others, have been documented. Taking St. John’s wort with certain antidepressants may lead to increased serotonin-related side effects, which may be potentially serious.

warfarin · HOS-085950 · Beziehung HOS-368733 · Originalquelle ↗

St. John's Wort · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 18082–18615 (Unicode-Codepoints).

St. John’s wort has an overall high risk of drug interaction because it is a potent inducer of both cytochrome P-450 enzymes and intestinal P-glycoprotein. Clinically significant interactions between St. John’s wort and the immunosuppressant drug cyclosporine, the antiretroviral agent indinavir, oral contraceptives, warfarin, digoxin, and benzodiazepines, among others, have been documented. Taking St. John’s wort with certain antidepressants may lead to increased serotonin-related side effects, which may be potentially serious.

digoxin · HOS-086172 · Beziehung HOS-368734 · Originalquelle ↗

St. John's Wort · Abgerufen: 27.10.2026. Schweregrad: nicht bewertet. Quellenspanne: 18082–18615 (Unicode-Codepoints).